Videos tagged genetic
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Turning Off Genes With The Flick Of A Switch
What happens if you can switch human genes off and on? Jim Collins, a College of Engineering biomedical engineering professor and a University professor, applied dynamical systems theory to the workings of physiological systems to answer that [...]important question for medical research. Collins is also the codirector of BU's Center for BioDynamics, and his laboratory there, the Applied Biodynamics Laboratory, has developed the world's first genetic toggle switch to find out.
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Health Communications in :60
As a grad student researching her master's thesis at a Toronto clinic in the early 1990s, Catharine Wang remembers watching women being tested for the newly cloned BRCA-1 gene, a risk indicator for breast cancer. At the time, the genetic science was [...]cutting edge and she saw patient upon patient unable to grasp the slew of radical information being thrown at them—about risks and probabilities. Some of them simply tuned out.
Today, the genetics-testing market is booming, with private companies are offering DNA tests for individuals at affordable prices. But it's not one-size-fits-all, Wang cautions. And context is critical. Multiple factors, such as lifestyle and environment, enter into the risk equation, not just hereditary probabilities, which more often than not land in a gray area. Wang's ongoing research, funded by the National Human Genome Research Institute (NHGRI) and the National Cancer Institute (NCI), is examining methods to effectively communicate genetic and environmental risk information for public health promotion and disease prevention.
"The rapid pace at which we're understanding the genetic causes of human diseases is mind-boggling," she says. "It's almost like information overload. If we can empower patients to be better communicators, they can take control over their health."
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