Neutrophils in a New Light: Emerging Roles in Inflammation

Neutrophils are among the most abundant and evolutionarily conserved components of the innate immune system, long recognized for their frontline role in microbial defense and acute inflammation. However, our understanding of these cells has significantly evolved. Beyond their classical functions, neutrophils are now appreciated as highly plastic and multifunctional cells with the capacity to influence a wide range of immune responses, including those involved in chronic and sterile inflammation, tissue repair, autoimmunity, and even cancer. This Article Collection highlights the growing complexity of neutrophil biology and its implications for understanding and treating inflammatory diseases.