Back to Journals » Open Access Journal of Clinical Trials
ISSN: 1179-1519
- View all (126)
- Volume 17, 2025 (4)
- Volume 16, 2024 (5)
- Volume 15, 2023 (1)
- Volume 14, 2022 (3)
- Volume 13, 2021 (6)
- Volume 12, 2020 (6)
- Volume 11, 2019 (6)
- Volume 10, 2018 (5)
- Volume 9, 2017 (8)
- Volume 8, 2016 (6)
- Volume 7, 2015 (8)
- Volume 6, 2014 (14)
- Volume 5, 2013 (14)
- Volume 4, 2012 (7)
- Volume 3, 2011 (11)
- Volume 2, 2010 (18)
- Volume 1, 2009 (4)
Journal Articles:
- 126 records -
The Adjunctive Efficacy of Fuzheng Huayu Tablet on Portal Hypertension with HBV Related Cirrhosis: A Protocol for a Multicenter Randomized Controlled Trial
Li Z, Guo Y, Huang J, Lv J, Liu C
Open Access Journal of Clinical Trials 2025, 17:51-61
Published Date: 3 June 2025

Overcoming Barriers in Incentive Management: Organizational Empowerment Enhancing Patient Engagement in Clinical Research


Stamenovic M
Open Access Journal of Clinical Trials 2025, 17:35-49
Published Date: 29 April 2025
Bridging the Past and Future of Clinical Data Management: The Transformative Impact of Artificial Intelligence
Musik S, Sasin-Kurowska J, Panczyk M
Open Access Journal of Clinical Trials 2025, 17:15-33
Published Date: 11 April 2025
Advancements in Managing Anthracycline-Induced Cardiotoxicity: Insights from Interventional Clinical Trials
Zhao M, Zhang X, Zhou D, Song J
Open Access Journal of Clinical Trials 2025, 17:1-14
Published Date: 30 January 2025
Understanding the Practical and Psychological Barriers to Clinical Trial Diversity and Accessibility
Parkhurst KL, Froment A
Open Access Journal of Clinical Trials 2024, 16:49-55
Published Date: 11 December 2024
Long Term Follow Up of Antibody Titres Against SARS-CoV-2 6 Months After Primary Protein Subunit COVID-19 Vaccination (ZF2001) in Indonesian Adults and Older Adults
Girsang RT, Fadlyana E, Rusmil K, Dwi Putra MG, Utami RK, Putri AD, Sukandar H
Open Access Journal of Clinical Trials 2024, 16:41-48
Published Date: 30 July 2024
Assessing Compliance and Satisfaction Among Participants in Clinical Trials on Traditional Chinese Medicine
Xiao S, Androulakis A, Skelton WD, Quan IL, Cheng J, Wang Y, Zhu X, Zhang H
Open Access Journal of Clinical Trials 2024, 16:23-39
Published Date: 18 June 2024
Evaluation of a Newly Developed Transdiagnostic Cognitive Behavioral Therapy Group to Promote Healthy Aging Among Older People with HIV: Study Protocol for a Pilot Randomized Controlled Trial
Foley JD, Bernier LB, Schiavo S, Davis MJ, Batchelder AW
Open Access Journal of Clinical Trials 2024, 16:11-21
Published Date: 11 June 2024
Center with or Without a Coordinator? The Coordinator as an Integral Part of a Research Team
Gudewicz I, Hajtuch J, Zaucha R
Open Access Journal of Clinical Trials 2024, 16:1-9
Published Date: 21 May 2024

A Multidomain Intervention Program for Older People with Dementia: A Pilot Study
Xuan Nguyen T, Thi Thanh Vu H, Nguyen T, Esterman A, Viet Tran L, Thillainadesan J, Naganathan V, Brodaty H, Trung Nguyen A
Open Access Journal of Clinical Trials 2023, 15:1-10
Published Date: 17 April 2023

Randomized Clinical Trial Comparing Insulin Fast Dissolving Films versus Control Group for Anosmic Patients for Improving Their Health and Social Qualities of Life
Mohamad SA, Sayed SM, Sadek AA, Badawi AM
Open Access Journal of Clinical Trials 2022, 14:25-33
Published Date: 23 December 2022

Treatment of Oropharyngeal Symptoms: A Prospective, Single-Dose, Placebo-Controlled, Randomized Clinical Trial
Kapoor K, Wilhelm D, Neumeister C, Götz MR, Schwantes U, Bleckert G, Gerstenmaier L, Jambrecina A
Open Access Journal of Clinical Trials 2022, 14:11-23
Published Date: 18 March 2022


Post-Trial Considerations for an Early Phase Optogenetic Trial in the Human Brain
White M, Whittaker RG
Open Access Journal of Clinical Trials 2022, 14:1-9
Published Date: 2 February 2022

Reviewing Treatments for Cocaine Consume Problems: The Gabapentinoid Alternative
Quintero Garzola GC
Open Access Journal of Clinical Trials 2021, 13:45-60
Published Date: 23 September 2021

Social Support Intervention for Self-Management of Type 2 Diabetes Mellitus: Study Protocol for a Randomized Controlled Trial
Garizábalo-Dávila CM, Rodríguez-Acelas AL, Mattiello R, Cañon-Montañez W
Open Access Journal of Clinical Trials 2021, 13:37-43
Published Date: 26 July 2021

Impacts of Research Staff Burnout for a National Large Scale Pragmatic Clinical Trial
Majkut Klint A, McPherson J, Tella A, Vang W, Raju S, Windschitl R, Ishani A
Open Access Journal of Clinical Trials 2021, 13:31-35
Published Date: 5 July 2021

Intensive Home Blood Pressure Lowering in Advanced Chronic Kidney Disease: A Pilot Randomized Controlled Trial Protocol
Bae SR, McCulloch CE, Hsu RK, Ku E
Open Access Journal of Clinical Trials 2021, 13:21-29
Published Date: 24 June 2021


Clinical Efficacy of an Osmotic, Antiviral and Anti-Inflammatory Polymeric Nasal Film to Treat Covid-19 Early-Phase Respiratory Symptoms


Shrivastava R, Vijay M, Maneby N, Shrivastava R
Open Access Journal of Clinical Trials 2021, 13:11-20
Published Date: 18 May 2021

Effectiveness of a Structured Nutrition Education Course for Caregivers of Children and Adolescents with Type 1 Diabetes in Improving Glycemic and Dietary Outcomes: A Cluster-Randomized Controlled Trial Protocol
Ndahura NB, Munga J, Kimiywe J, Mupere E
Open Access Journal of Clinical Trials 2021, 13:1-10
Published Date: 19 April 2021

Terminated Interventional Trials in the Clinical Trial Registry of India Database: An Analysis to Evaluate the Reasons for Termination
Dutta S, Kaur R, Haque M, Bhardwaj P, Saxena D, Rahman NAA, Lugova H, Jahan D, Islam S, Chowdhury TS, Charan J
Open Access Journal of Clinical Trials 2020, 12:61-70
Published Date: 3 December 2020

The Use of Gabapentin for the Treatment of Alcohol and Tobacco Use Disorders: A Review
Quintero Garzola GC
Open Access Journal of Clinical Trials 2020, 12:43-60
Published Date: 24 September 2020

Taking Optogenetics into the Human Brain: Opportunities and Challenges in Clinical Trial Design
White M, Mackay M, Whittaker RG
Open Access Journal of Clinical Trials 2020, 12:33-41
Published Date: 25 August 2020

Effectiveness of Body Awareness Therapy in Stroke Survivors: A Systematic Review of Randomized Controlled Trials
Alamer A, Getie K, Melese H, Mazea H
Open Access Journal of Clinical Trials 2020, 12:23-32
Published Date: 17 August 2020

Remdesivir is Effective for Moderately Severe Patients: A Re-Analysis of the First Double-Blind, Placebo-Controlled, Randomized Trial on Remdesivir for Treatment of Severe COVID-19 Patients Conducted in Wuhan City
Shih WJ, Shen X, Zhang P, Xie T
Open Access Journal of Clinical Trials 2020, 12:15-21
Published Date: 30 July 2020

MCLENA-1: A Phase II Clinical Trial for the Assessment of Safety, Tolerability, and Efficacy of Lenalidomide in Patients with Mild Cognitive Impairment Due to Alzheimer’s Disease
Decourt B, Wilson J, Ritter A, Dardis C, DiFilippo FP, Zhuang X, Cordes D, Lee G, Fulkerson ND, St Rose T, Hartley K, Sabbagh MN
Open Access Journal of Clinical Trials 2020, 12:1-13
Published Date: 7 January 2020

Verified Hepatorenal Syndrome Reversal As A Robust Multi-Component Primary End Point: The CONFIRM Study Trial Design
Jamil K, Pappas SC, Wong F, Sanyal AJ
Open Access Journal of Clinical Trials 2019, 11:67-73
Published Date: 22 November 2019

The Challenges In Conducting Research Studies In Arabic Countries
Sheblaq N, Al Najjar A
Open Access Journal of Clinical Trials 2019, 11:57-66
Published Date: 7 November 2019

The European Medicines Agency Clinical Data Website Enables Insights Into Clinical Development Timelines And Strategy
Lehmann S, Allard R, Boehler YB
Open Access Journal of Clinical Trials 2019, 11:37-56
Published Date: 15 October 2019

An evaluation of informed consent comprehension by adult trial participants in South Africa at the time of providing consent for clinical trial participation and a review of the literature
Burgess LJ, Gerber B, Coetzee K, Terblanche M, Agar G, Kotze TJ
Open Access Journal of Clinical Trials 2019, 11:19-35
Published Date: 8 July 2019

Cost comparison analysis of laparoscopic versus open aortobifemoral bypass surgery: a randomized controlled trial
Sahba M, Krog AH, Pettersen EM, Wisløff T, Rogne KG, Sundhagen JO, Kazmi SSH
Open Access Journal of Clinical Trials 2019, 11:11-18
Published Date: 19 June 2019

Effects of pain on cognitive function and mobility
Moreira SA, Novak P
Open Access Journal of Clinical Trials 2019, 11:1-10
Published Date: 25 March 2019


Selective enhancement of focused attention by Alpinia galanga in subjects with moderate caffeine consumption


Srivastava S
Open Access Journal of Clinical Trials 2018, 10:43-49
Published Date: 6 September 2018

Computerized cognitive training to improve mood in senior living settings: design of a randomized controlled trial

Smith M, Jones MP, Dotson MM, Wolinsky FD
Open Access Journal of Clinical Trials 2018, 10:29-41
Published Date: 26 April 2018

Placebo-only-controlled versus active-controlled trials of new drugs for nine common life-threatening diseases
Sorscher S, AbuDagga A, Almashat S, Carome MA, Wolfe SM
Open Access Journal of Clinical Trials 2018, 10:19-28
Published Date: 24 April 2018

Open-label Phase II study of everolimus plus endocrine therapy in postmenopausal women with ER-positive and HER2-negative metastatic breast cancer (Chloe trial)
Shimoi T, Shimomura A, Shien T, Uemura Y, Kato H, Kitada M, Toyama T, Aihara T, Mukai H
Open Access Journal of Clinical Trials 2018, 10:13-18
Published Date: 16 February 2018

Life Enhancing Activities for Family Caregivers of people with dementia: protocol for a randomized controlled trial of a positive affect skills intervention
Verstaen A, Moskowitz JT, Snowberg KE, Merrilees J, Dowling GA
Open Access Journal of Clinical Trials 2018, 10:1-12
Published Date: 7 February 2018

Randomized response surface pathway design with odd response outcomes in a Latin Square designed study
Holand T, Ellingsen K, Dewi S, Larsen S
Open Access Journal of Clinical Trials 2017, 9:75-84
Published Date: 14 September 2017

A randomized controlled trial to improve heart failure disparities: the Mālama Puʻuwai (caring for heart) Study
Mau MKLM, Lim E, Kaholokula JK, Loui TMU, Cheng Y, Seto TB
Open Access Journal of Clinical Trials 2017, 9:65-74
Published Date: 3 August 2017

Informing primary care physicians of patients' involvement in clinical trials carried out at a specialist care level
Schoenenberger-Arnaiz JA, Solanilla-Puertolas M, Acer-Puig M, Gomez-Arbones J
Open Access Journal of Clinical Trials 2017, 9:59-64
Published Date: 27 July 2017

Efficacy and safety of two fast-absorbing formulations of paracetamol in combination with caffeine for episodic tension-type headache: results from two randomized placebo- and active-controlled trials
Yue Y, Reed KD, Shneyer L, Liu DJ
Open Access Journal of Clinical Trials 2017, 9:41-57
Published Date: 26 June 2017

Evaluation of medication errors with implementation of electronic health record technology in the medical intensive care unit
Liao TV, Rabinovich M, Abraham P, Perez S, DiPlotti C, Han JE, Martin GS, Honig E
Open Access Journal of Clinical Trials 2017, 9:31-40
Published Date: 23 May 2017

The role of functional, social, and mobility dynamics in facilitating older African Americans participation in clinical research
Shapiro ET, Schamel JT, Parker KA, Randall LA, Frew PM
Open Access Journal of Clinical Trials 2017, 9:21-30
Published Date: 7 April 2017

A pilot study of a smoking cessation intervention for women living with HIV: study protocol
Kim SS, Darwish S, Lee SA, DeMarco RF
Open Access Journal of Clinical Trials 2017, 9:11-20
Published Date: 7 February 2017

Phase I dose-escalation trial of intravaginal curcumin in women for cervical dysplasia
Gattoc L, Frew PM, Thomas SN, Easley KA, Ward L, Chow HHS, Ura CA, Flowers L
Open Access Journal of Clinical Trials 2017, 9:1-10
Published Date: 22 December 2016

Quality of clinical trials for selected priority mental and neurological disorders in sub-Saharan Africa: a systematic review
Mulugeta A, Medhin G, Yimer G, Jemal R, Fekadu A
Open Access Journal of Clinical Trials 2016, 8:43-52
Published Date: 7 December 2016

Development of a randomized two-dimensional response surface pathway design with two interventional and one response variables
Holand T, Dewi S, Larsen S
Open Access Journal of Clinical Trials 2016, 8:33-42
Published Date: 13 October 2016


Rain dance: the role of randomization in clinical trials


Diniz JB, Fossaluza V, Pereira CAB, Wechsler S
Open Access Journal of Clinical Trials 2016, 8:21-32
Published Date: 13 July 2016

An international, multicenter, observational survey to evaluate diabetes control in subjects using insulin for the treatment of type 1 and type 2 diabetes mellitus in the Czech Republic and Slovak Republic: study protocol for a cross-sectional survey
Brož J, Zdarska DJ, Urbanova J, Brabec M, Krivska B, Donicova V, Stepanova R, Martinka E, Kvapil M
Open Access Journal of Clinical Trials 2016, 8:13-20
Published Date: 9 June 2016

Protocol-writing support conferences for investigator-initiated clinical trials
Goto M, Muragaki Y, Aruga A
Open Access Journal of Clinical Trials 2016, 8:7-12
Published Date: 12 April 2016

Neuropsychiatric symptoms in dementia and the effects of Ginkgo biloba extract EGb 761® treatment: additional results from a 24-week randomized, placebo-controlled trial
Nacu A, Hoerr R
Open Access Journal of Clinical Trials 2016, 8:1-6
Published Date: 18 January 2016