Journal of Inflammation Research

Dove Medical Press is pleased to invite you to submit your research to an upcoming Article Collection on "Anti-inflammatory Biologics – A Game Changer for Chronic Inflammation", in the Journal of Inflammation Research.

This Collection, edited by the Editor-In-Chief Prof. Ning Quan, is part of the new Game Changer series of Article Collections, focusing on breakthrough therapies, drugs, and technologies that have significantly altered the standard of care, leading to game-changing improvements in patient outcomes.

Chronic inflammation is the hallmark of many diseases. These conditions can be crippling to patients. Traditional anti-inflammatory drugs, such as non-steroidal anti-inflammatory drugs (NSAIDs) or corticosteroids, are non-specific, causing further systemic problems with continued use. By contrast, biologic therapies harness the specificity necessary to relieve inflammation while also reducing off-target and non-specific effects.

While this call is open to receive manuscripts highlighting all anti-inflammatory biologics, the Editors are particularly interested in manuscripts relating to the following areas:

• Tumor necrosis factor inhibitors
• Interleukin inhibitors
• Monoclonal antibody specificity studies
• Novel mechanisms of action of new candidate biologics
• The role of biosimilars in treating inflammatory disease
• Indications and contraindications
• Cell-based therapies to quell inflammation

Submitting authors are eligible for a 20% discount on the Article Publishing charge by applying the following code at the point of submission: OTIPZ. If you have any queries regarding the Article Collection or would like to discuss a submission, then please email the Commissioning Editor Ashley Ambros ([email protected]). Papers published within the Game Changer series will benefit from additional promotional activities across Taylor and Francis, increasing the discoverability and visibility of your research.

All manuscripts submitted to this Article Collection will undergo a full peer-review. Please review the journal’s aims and scope and author submission instructions prior to submitting a manuscript. Please submit your manuscript on our website. The deadline for submitting a manuscript is 1 April 2026.

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Dove Medical Press is pleased to invite you to submit your research to an upcoming Article Collection on "Targeting the IL-4/IL-13 Axis in the Treatment of Type 2 Inflammation", in the Journal of Inflammation Research.

This Collection, edited by the Editor-In-Chief Prof. Ning Quan, is part of the new Game Changer series of Article Collections, focusing on breakthrough therapies, drugs, and technologies that have significantly altered the standard of care, leading to game-changing improvements in patient outcomes.

Type 2 inflammation occurs when immune cells, including eosinophils and mast cells, are activated, producing the cytokine IL-4 and Il-13. These cytokines are responsible for signaling the production of eosinophils, mast cells, and IgE antibodies, that lead to the release of more pro-inflammatory cytokines. Type 2 inflammatory conditions affect 10-30% of the global population, and include common conditions such as allergy, asthma, eczema, and eosinophilic esophagitis. By targeting IL-4 and IL-13, overactive immune systems can be regulated, and many patients will see a better quality of life.

While this call is open to receive manuscripts highlighting all aspects of drugs targeting the IL-4/Il-13 axis, the Editors are particularly interested in manuscripts relating to the following areas:

• Clinical studies on the efficacy and safety of IL-4 and/or IL-13 inhibitors
• Novel drug mechanistic actions
• Biologics directed against cells or pathways involved in the IL-4/IL-13 axis
• New drug candidates directed against IL-4 and/or IL-13
• Tailoring treatment in individuals with multiple Type 2 inflammatory conditions
• Drugs to treat non-allergic type 2 inflammation, such as nasal polyps
• Treatment strategies and potential side effects

Submitting authors are eligible for a 20% discount on the Article Publishing charge by applying the following code at the point of submission: YXVCF. If you have any queries regarding the Article Collection or would like to discuss a submission, then please email the Commissioning Editor Ashley Ambros ([email protected]). Papers published within the Game Changer series will benefit from additional promotional activities across Taylor and Francis, increasing the discoverability and visibility of your research.

All manuscripts submitted to this Article Collection will undergo a full peer-review. Please review the journal’s aims and scope and author submission instructions prior to submitting a manuscript. 

Please submit your manuscript on our website. The deadline for submitting a manuscript is 1 April 2026.

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Dove Medical Press is pleased to invite you to submit your research to an upcoming Article Collection on "The Translation of Discovery: Cutting Edge Research to Study Airway Inflammation", in the Journal of Inflammation Research, with Guest Advisors Dr. Reynold Panettieri and Dr. Cynthia Koziol-White.

All currently-approved pharmaceuticals have had the same humble beginnings – a hypothesis and experiment in a laboratory. Translational research is a crucial component in drug discovery, though results obtained using in vivo animal models such as mice do not always translate well from bench to bedside. Moreover, technological advancements have made it possible to study aspects of inflammatory processes we never thought possible.

The field of translational immunology allows researchers to learn more about inflammatory processes contributing to airway disorders such as asthma and allergy. These inflammatory airway disorders are found in over 25 million individuals worldwide, and severe inflammatory responses can lead to hospitalization and even death. Preclinical and clinical research have led to the identification and production of drugs with new therapeutic targets, such as interleukin-4, interleukin-1, interleukin-33 and thymic stromal lymphopoietin.

The Guest Advisors welcome relevant clinical Original Research, Reviews, Reports, Hypothesis Formation, Commentaries, and Expert Opinions. These articles may pertain broadly to translational immunology of asthma and allergy, though special attention will be given to the following subareas:

1. Novel in vitro, in vivo, and ex vivo models to study airway inflammation such as organoids

2. New therapeutic targets

3. Genome-wide CRISPR screening for drug discovery

4. Translational information derived from Single-cell RNA seq

5. Whole tissue dynamics using spatial transcriptomics

6. Exome sequencing

7. Immunological synapses between immune cells and structural/mesenchymal cells

All manuscripts submitted to this Article Collection will undergo a full peer-review. Please review the journal’s aims and scope and author submission instructions prior to submitting a manuscript.

Please submit your manuscript on our website, using the promo code 79538 for a 10% discount on the Article Processing Charge. The deadline for submitting a manuscript is 31 March 2026.

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Dove Medical Press is pleased to invite you to submit your research to an upcoming Article Collection on "Omics, Microbiome, and Artificial Intelligence: Novel Insights into Human Disease-Associated Inflammatory Responses", in the Journal of Inflammation Research, with Guest Advisors Dr. Swarna Kanchan and Dr. Minu Kesheri.

Understanding the integrative boost powered by omics technologies, human microbiota, and artificial intelligence is transforming our approach to various human diseases. Omics technologies such as epigenomics, genomics, transcriptomics, proteomics, and metabolomics provide comprehensive molecular insights for both host and microbial factors inducing inflammation, especially the dysregulated and chronic inflammation leading to various human diseases. The gut microbiota plays a pivotal role in modulating the immune system often linked to the onset and progression of various inflammatory and autoimmune diseases and maintaining homeostasis. Recent advances in multi-omics integration, powered by artificial intelligence, are enabling researchers to unravel complex host-microbe interactions, identify disease-associated molecular signatures such as driver genes and molecular pathways, and predict patient-specific responses to various therapies advancing precision medicine by facilitating earlier diagnosis, personalized treatment strategies, and improved outcomes for individuals affected by inflammatory conditions.

This topic is important because it addresses the growing need for comprehensive strategies to tackle inflammatory diseases responsible for one of the major causes of morbidity and mortality worldwide. By integrating multi-omics data, understanding the role of the microbiota, and leveraging the capabilities of artificial intelligence, researchers can gain exceptional insights into the complex mechanisms driving inflammatory responses. A comprehensive understanding of the molecular mechanisms, microbial influences, and individual variations is essential for developing effective therapies. This interdisciplinary approach has the potential to identify unique biomarkers, new therapeutic targets to develop novel and personalized medicines, and improve patient outcomes in a wide range of conditions, including inflammatory, autoimmune disorders, metabolic diseases, and cancer. Ultimately, a deeper understanding of these interactions will lead to more effective and targeted treatments, reducing the burden of inflammatory diseases on individuals and healthcare systems.

This Article Collection delves into how multi-omics approaches, gut microbiota dynamics, and artificial intelligence (AI) synergize to provide novel insights into inflammatory responses and mechanisms. The journal welcomes original research manuscripts, reviews, hypothesis formation, expert opinions, etc., relating to all aspects of inflammation.

Potential Subtopics
• Multi-Omics Profiling of Inflammatory Diseases: Integrating epigenomics, genomics, transcriptomics, proteomics, and metabolomics to identify key molecular signatures associated with different inflammatory conditions leading to various diseases.
• Microbiota's Role in Inflammation: Investigating how gut microbiota composition and function influence inflammation (dysregulated and chronic), including various metagenomics studies on dysbiosis, and host-microbe interactions.
• AI-Driven Analysis of Inflammatory Data: Applying machine learning and bioinformatics to analyze complex omics and clinical data, predict disease biomarkers, identify potential therapeutic targets, develop diagnostic personalized therapies, and improve patient management
• Novel Therapeutic Strategies Targeting Inflammation: Exploring new treatments, including precision medicine approaches, that modulate inflammatory responses by targeting specific molecular pathways or the gut microbiota.

Keywords

1. Multi-Omics
2. Microbiome
3. Machine learning
4. Precision Health
5. Inflammatory Diseases

All manuscripts submitted to this Article Collection will undergo a full peer-review. Please review the journal’s aims and scope and author submission instructions prior to submitting a manuscript.

Please submit your manuscript on our website, using the promo code 08045 to indicate that the manuscript is intended for this Article Collection. The deadline for submitting a manuscript is 15 November 2025.

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Dove Medical Press is pleased to invite you to submit your research to an upcoming Article Collection on "Cellular and Molecular Drivers of Lung Inflammation in Respiratory Diseases", in the Journal of Inflammation Research.

Lung inflammation is a hallmark characteristic feature of many respiratory diseases, from asthma and chronic obstructive pulmonary disease (COPD) to pulmonary fibrosis and acute respiratory distress syndrome (ARDS). While inflammation serves as a protective role in response to infection or injury, dysregulated or persistent inflammatory responses can lead to progressive lung damage and impaired respiratory structure and function. Understanding the cellular and molecular drivers behind lung inflammation is crucial for developing targeted therapies that can modulate these pathways without compromising host defense. This topic explores the intricate network of immune and structural cells, signaling pathways, and other cofounding factors that orchestrate inflammatory responses in the lung. This study will offer valuable insight into both disease mechanisms and potential intervention points.

This topic is important because it establishes the foundational understanding of lung inflammation, a key driver of the onset, progression, and severity of numerous respiratory diseases that together pose a significant global health burden.
Studying this topic also matters as it provides following additional advantages:
• Better Understanding of Disease Mechanisms
• Development of Targeted Therapies
• Early Diagnosis and Biomarkers tools
• Understanding Environmental and Infectious Triggering agent

The subject of this Collection, "Cellular and Molecular Drivers of Lung Inflammation in Respiratory Diseases," explores the complex cellular and molecular processes that drive and regulate lung inflammation. It covers key subtopics including immune cell activation, structural cells dysfunction, cytokine and chemokine signaling, and the impact of environmental and infectious triggers on pulmonary inflammation. Special attention will also be given to emerging therapeutic targets and biomarker discovery. This scope is well-aligned with the Journal of Inflammation Research, which emphasizes cutting-edge studies on inflammation-related processes. The ail of this collection will be to encourage the submission of original research articles, comprehensive reviews, and brief reports that will provide new insights into the cellular and molecular understanding of lung inflammation in both acute and chronic respiratory diseases.

Keywords

1. Lung inflammation
2. Respiratory diseases
3. Immune cell signaling
4. Cytokines and chemokines
5. Biomarkers of lung disease

All manuscripts submitted to this Article Collection will undergo a full peer-review. Please review the journal’s aims and scope and author submission instructions prior to submitting a manuscript.

Please submit your manuscript on our website, using the promo code 5DF61 to indicate that the manuscript is intended for this Article Collection. The deadline for submitting a manuscript is 2 March 2026.

Guest Advisors

Dr. Ashish Kumar, North Dakota State University

[email protected]

I am a Doctoral Graduate Research Assistant in pharmaceutical sciences, specializing in the pathophysiology of asthma. My research explores the dynamic relationship between lung physiology and hormonal influences in disease conditions, aiming to advance respiratory pharmacology and personalized medicine.

Dr. Nilesh Sudhakar Ambhore,University of Minnesota

[email protected]

I am a dedicated and self-motivated research scientist with over 8 years of extensive experience in pharmacology, molecular biology, small molecule drug discovery, and target validation. My proven expertise encompasses the entire preclinical drug development process, including development of in vivo disease models, mechanism of action investigation, endpoint analysis, and disease modelling.

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Dove Medical Press is pleased to invite you to submit your research to an upcoming Article Collection on "Neutrophils in a New Light: Emerging Roles in Inflammation", in the Journal of Inflammation Research.

Neutrophils are among the most abundant and evolutionarily conserved components of the innate immune system, long recognized for their frontline role in microbial defense and acute inflammation. However, our understanding of these cells has significantly evolved. Beyond their classical functions, neutrophils are now appreciated as highly plastic and multifunctional cells with the capacity to influence a wide range of immune responses, including those involved in chronic and sterile inflammation, tissue repair, autoimmunity, and even cancer.

This proposed Article Collection of the Journal of Inflammation Research aims to highlight the growing complexity of neutrophil biology and its implications for understanding and treating inflammatory diseases. By assembling a focused collection of high-quality original research articles, reviews, and short communications, this issue will provide readers with a comprehensive and up-to-date overview of the novel roles of neutrophils across diverse inflammatory contexts.

The field of neutrophil research is currently undergoing a paradigm shift. Advances in single-cell RNA sequencing, in vivo imaging, and functional assays have revealed striking heterogeneity among neutrophil populations, suggesting that they are far from being a homogenous cell type. Moreover, their ability to engage in crosstalk with other immune cells, influence adaptive responses, shedding neutrophil extracellular traps (NETs), and contribute to chronic inflammatory states has far-reaching implications for disease progression and therapy.

Despite this, neutrophils remain understudied compared to other immune cells, particularly in chronic disease settings where their roles are less obvious but no less critical. A dedicated special issue in the Journal of Inflammation Research would provide a much-needed platform for consolidating recent discoveries, showcasing state-of-the-art methodologies, and highlighting clinical relevance. Such an issue is well aligned with the journal’s mission to advance understanding of inflammatory mechanisms and foster translational insights into inflammation-related disorders.

This Article Collection will explore the evolving landscape of neutrophil biology with particular emphasis on novel and disease-relevant functions. The field in which submissions are welcomed address the following (but not limited to) subtopics:
1) Neutrophil heterogeneity and plasticity: Insights from single-cell and spatial profiling.
2) Neutrophil roles in chronic inflammation and autoimmunity: Contributions to diseases such as lupus, rheumatoid arthritis, and vasculitis.
3) NETs in inflammation: Molecular mechanisms, regulation, and pathological consequences.
4) Tissue-specific neutrophil behavior: Adaptation and function in lungs, liver, gut, CNS, and tumors.
5) Neutrophil interactions with adaptive immunity: Mechanisms of T cell modulation and antigen presentation.
6) Neutrophils in infection and viral inflammation: Including roles in COVID-19, sepsis, and chronic infections.

This Article Collection will serve as a comprehensive reference for scientists and clinicians working across immunology, inflammation, infectious disease, and translational medicine. By focusing on neutrophils, a cell type once considered simple but now recognized as highly influential, this issue aims to stimulate further research and innovation in the field of inflammation.

Keywords

1. Neutrophils Biology
2. Innate Immunity
3. Inflammation Resolution
4. Neutrophil Heterogeneity
5. Neutrophil Extracellular Traps (NETs)

All manuscripts submitted to this Article Collection will undergo a full peer-review. Please review the journal’s aims and scope and author submission instructions prior to submitting a manuscript.

Please submit your manuscript on our website, using the promo code 5480B to indicate that the manuscript is intended for this Article Collection. The deadline for submitting a manuscript is 2 March 2026.

Guest Advisor

Dr. Tomasz W Kaminski, Thrombosis and Hemostasis Program, Versiti Blood Research Institute, Milwaukee, WI

[email protected]

Tomasz W. Kaminski earned his doctoral degree from the Medical University of Bialystok, Poland. During his PhD training, he focused on studying hemostasis disturbances in chronic kidney disease. He joined the Sundd Lab as a postdoctoral associate in 2019. Dr. Kaminski’s research centers on innate immune mechanisms in platelets and neutrophils, as well as the pathophysiology of thrombo-inflammation. He employs state-of-the-art intravital microscopy techniques to capture real-time interactions between neutrophils and platelets during the initial phases of immune system activation. His work exhibits a truly interdisciplinary nature, as he investigates the neutrophil and platelet biology in hemophilic arthropathy, sickle cell disease and influenza. Dr. Kaminski has been recognized with numerous awards from both national and international societies and institutions. Furthermore, his research endeavors receive support from external funding sources.

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Dove Medical Press is pleased to invite you to submit your research to an upcoming Article Collection on "Integrating Artificial Intelligence into Inflammation and Cancer Immunology: From Biomarkers Discovery and Mechanistic Insights to Precision Therapeutics", in the Journal of Inflammation Research.

Inflammation exerts a complex and context-dependent influence on both oncogenesis and the efficacy of cancer therapies. Acute inflammatory responses may enhance anti-tumor immunity; however, chronic inflammation is more commonly implicated in tumor initiation, progression, and the facilitation of immune evasion. Persistent inflammatory signaling contributes to the development of an immunosuppressive tumor microenvironment (TME) by promoting the infiltration of immunoregulatory cell populations, including regulatory T cells, myeloid-derived suppressor cells, and M2-polarized macrophages. This immunosuppressive milieu hinders the therapeutic effectiveness of immune checkpoint inhibitors and adoptive cell therapies such as chimeric antigen receptor T cells. Inflammatory cytokines such as IL-6, IFN-, and TNF-α also play dual roles, with context-dependent capacities to either promote immune resistance or augment immune activation.

Consequently, the modulation of inflammatory pathways holds promise for the development of patient-specific therapeutic strategies aimed at enhancing responses to anti-cancer treatments. For example, the combination of anti-inflammatory agents with immune checkpoint inhibitors may be particularly beneficial in patients exhibiting elevated baseline levels of inflammation. Among the most promising anti-inflammatory approaches is the use of epigenetic inhibitors, including histone deacetylase (HDAC) inhibitors and DNA methyltransferase (DNMT) inhibitors, which have demonstrated synergistic potential when used in combination with immunotherapies to overcome resistance mechanisms. Importantly, the identification of inflammation-associated biomarkers is essential for effective patient stratification. Such biomarkers would enable the rational design of combinatorial treatment regimens and improve the predictive capacity for therapeutic responses in the context of cancer immunotherapy.

The complex regulatory networks that control inflammation within TME are pivotal to the rational design of combinatorial strategies. Recent advances in artificial intelligence (AI), multi-omics technologies, and computational biology now offer powerful tools for the identification and validation of inflammation-associated biomarkers, as well as for elucidating the epigenetic alterations that drive their activation. These insights can be leveraged to inform the development of targeted therapeutic approaches, thereby facilitating the identification of individuals most likely to benefit from specific immunoepigenetic interventions.

This Article Collection seeks interdisciplinary research that investigate the role and underlying mechanisms of epigenetic alterations in the regulation of inflammation and tumor immunity. We welcome original research articles, reviews, clinical trial studies, and case reports. Submissions are also encouraged that examine the application of AI in predicting therapeutic responses and guiding precision immuno-oncology strategies.

Keywords

1. Inflammation and Tumor Immunity
2. Epigenetic Modulation
3. Artificial Intelligence in Oncology
4. Tumor Microenvironment and Metabolism
5. Diagnostic and Prognostic Biomarkers

All manuscripts submitted to this Article Collection will undergo a full peer-review. Please review the journal’s aims and scope and author submission instructions prior to submitting a manuscript.

Please submit your manuscript on our website, using the promo code 34582 to indicate that the manuscript is intended for this Article Collection. The deadline for submitting a manuscript is 15 April 2026.

Please contact Ashley Ambros at [email protected] with any queries and discount codes regarding this Article Collection.

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