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ISSN: 2253-5969


       

Journal Articles:

- 792 records -

Original Research

Treatment Outcomes of Systemic Therapies for Infiltrative Hepatocellular Carcinoma

Chen PY, Chang CK, Chen BB, Hsu CH, Cheng AL, Shao YY

Journal of Hepatocellular Carcinoma 2025, 12:1221-1229

Published Date: 23 June 2025

Review

Application of Robotic Surgery in Hepatocellular Carcinoma

Li PH, Ding ZW, Ye YQ

Journal of Hepatocellular Carcinoma 2025, 12:1217-1220

Published Date: 19 June 2025

Original Research

Hepatic Arterial Infusion Chemotherapy Combined Apatinib/Camrelizumab for Recurrent Hepatocellular Carcinoma After Hepatectomy

Zheng X, Qian K

Journal of Hepatocellular Carcinoma 2025, 12:1205-1215

Published Date: 17 June 2025

Original Research

In Situ Vaccination with Poly-ICLC Combined with Systemic Nivolumab for the Treatment of Unresectable Hepatocellular Carcinoma

Liang JD, Liang PC, Shun CT, Chen CH, Wu YM, Hsu YC, Lee YT, Yang PM, Huang GT, Salazar AM, Lee HS, Sheu JC, Weng MT

Journal of Hepatocellular Carcinoma 2025, 12:1191-1204

Published Date: 14 June 2025

Original Research

Intravoxel Incoherent Motion Improves the Accuracy of Preoperative Prediction of Vessels Encapsulating Tumor Clusters in Hepatocellular Carcinoma

Li M, Zhang G, Li J, Ren Y, Jin X, Ke Q, Guo C, Lv J, Lu H, Xu Y, Liang W, Quan X, Li X

Journal of Hepatocellular Carcinoma 2025, 12:1177-1190

Published Date: 11 June 2025

Original Research

Early Recurrence of Hepatocellular Carcinoma in Patients without Microscopic Vascular Invasion: Clinicopathological Characteristics and Risk Factors

Ngo HTT, Nguyen DD, Dang MX, Doan TTP, Thai TT

Journal of Hepatocellular Carcinoma 2025, 12:1167-1175

Published Date: 11 June 2025

Original Research

Genetic Variants of UGP2 and FBP2 in the Glycolysis Pathway Independently Predict Survival of Patients with HBV-Related Hepatocellular Carcinoma

Gong R, Qiu M, Liu Y, Cao J, Zhou Z, Lin Q, Jiang Y, Liang X, Wei Y, Wen Q, Chen P, Wei X, Wei J, Zhan S, Zhang R, Ye D, Yu H

Journal of Hepatocellular Carcinoma 2025, 12:1155-1166

Published Date: 7 June 2025

Original Research

Factor Analysis of the Effect of Hepatitis B-Related Liver Cancer Treatment Efficacy

Liu SW, Zhou Y, Feng XY, Hai L, Ma WL, Ma LN, Ding XC, Luo X

Journal of Hepatocellular Carcinoma 2025, 12:1141-1154

Published Date: 5 June 2025

Review

Radiomics and Deep Learning as Important Techniques of Artificial Intelligence — Diagnosing Perspectives in Cytokeratin 19 Positive Hepatocellular Carcinoma

Wang F, Yan C, Huang X, He J, Yang M, Xian D

Journal of Hepatocellular Carcinoma 2025, 12:1129-1140

Published Date: 5 June 2025

Original Research

Predicting Resistance and Survival of HCC Patients Post-HAIC: Based on Shapley Additive exPlanations and Machine Learning

Yao F, Miao J, Quan B, Li J, Tang B, Lu S, Yin X

Journal of Hepatocellular Carcinoma 2025, 12:1111-1128

Published Date: 31 May 2025

Original Research

Effectiveness and Safety of Systemic Therapy and Stereotactic Body Radiotherapy in Oligoprogressive and Oligometastatic Hepatocellular Carcinoma

Song Z, Zheng X, Wang H, Dong D, Zhu X, Geng J, Li S, Song M, Du R, Zhang Y, Liu Z, Cai Y, Li Y, Wang W

Journal of Hepatocellular Carcinoma 2025, 12:1097-1110

Published Date: 31 May 2025

Original Research

Intratumoral and Peritumoral Radiomics Based on DCE-MRI for Prediction of Microvascular Invasion Grading in Solitary Hepatocellular Carcinoma (≤3 cm)

Li Y, Li H, Feng Y, Lu L, Zhang J, Jia N

Journal of Hepatocellular Carcinoma 2025, 12:1083-1095

Published Date: 30 May 2025

Original Research

Spleen Volume Dynamics and Survival Outcomes in HCC Patients Undergoing Immune Checkpoint Inhibitors: A Retrospective Analysis

Fu X, Jiang S, Li Y, Guo Y, Gong B, Lou J, Li Y, Wang S, Sun Y, Ren Y, Chen Q, Yang L

Journal of Hepatocellular Carcinoma 2025, 12:1069-1082

Published Date: 30 May 2025

Original Research

Primary Prophylaxis for High-Risk Varices in Patients with Hepatocellular Carcinoma and Portal Vein Tumor Thrombus Delayed Hepatic Decompensation: A Retrospective, Propensity Score Matching Study

Chen YJ, Hou MC, Yang TC, Lee PC, Lu HS, Huang HC, Huang YH, Luo JC

Journal of Hepatocellular Carcinoma 2025, 12:1057-1067

Published Date: 28 May 2025

Clinical Trial Report

Adjuvant Lenvatinib for High-Risk CNLC IIb/IIIa Hepatocellular Carcinoma After Curative Hepatectomy: A Prospective Exploratory Study

Sun HC, Huang ZY, Wen T, Liu L, Zhu XD, Zhang E, Li C, Zhang X, Wang J, Fan J, Zhou J

Journal of Hepatocellular Carcinoma 2025, 12:1043-1056

Published Date: 22 May 2025

Original Research

Transarterial Chemoembolization, Molecular Targeted Treatments, and Programmed Death-(Ligand)1 Inhibitors, for Hepatocellular Carcinoma with Lung Metastasis: A Retrospective Cohort Study

Lu J, Chen X, Liu Y, Ding Y, Li B, Yang J, Peng W, Yang X

Journal of Hepatocellular Carcinoma 2025, 12:1031-1041

Published Date: 23 May 2025

Original Research

Combination of Hepatic Arterial Infusion Chemotherapy with Tyrosine Kinase Inhibitor Provides Better Survival in Advanced Hepatocellular Carcinoma Patients

Liu CW, Lin PT, Teng W, Chen WT, Su CW, Hsieh YC, Lin CC, Lin CY, Lin SM

Journal of Hepatocellular Carcinoma 2025, 12:1017-1029

Published Date: 21 May 2025

Original Research

Radiomics of Dynamic Contrast-Enhanced MRI for Predicting Radiation-Induced Hepatic Toxicity After Intensity Modulated Radiotherapy for Hepatocellular Carcinoma: A Machine Learning Predictive Model Based on the SHAP Methodology

Liu F, Chen L, Wu Q, Li L, Li J, Su T, Li J, Liang S, Qing L

Journal of Hepatocellular Carcinoma 2025, 12:999-1015

Published Date: 17 May 2025

Original Research

MRI Radiomics to Predict Early Treatment Response to TACE Combined with Lenvatinib Plus a PD-1 Inhibitor for Hepatocellular Carcinoma with Portal Vein Tumor Thrombus

Lu D, Zhou L, Zuo Z, Zhang Z, Zheng X, Weng J, Yu Z, Ji J, Xia J

Journal of Hepatocellular Carcinoma 2025, 12:985-998

Published Date: 16 May 2025

Original Research

Atezolizumab Plus Bevacizumab Combined with or without Transarterial Chemoembolization in the Treatment of Advanced Hepatocellular Carcinoma: A Single-Center Retrospective Study

Li J, Bai Y, Xiong F, Liu X, Hu J, Zhang G, Liu J, Wu S, Zheng C, Kan X

Journal of Hepatocellular Carcinoma 2025, 12:973-984

Published Date: 15 May 2025

Original Research

The Real-World Prevalence of Esophagogastric Varices, Bleeding, Emergency Room Visits, and Hospitalization Among Patients with Advanced Hepatocellular Carcinoma in the United States: A Retrospective Cohort Study

Parikh ND, Park NJ, Locker M, Chopra I, Yeaw J, Yu S

Journal of Hepatocellular Carcinoma 2025, 12:961-972

Published Date: 15 May 2025

Original Research

Can Intra-Operative Ablation-Specific Features Based on Ultrasound Fusion Imaging be Used to Predict Early Recurrence of Hepatocellular Carcinoma After Microwave Ablation: A Proof-of-Concept Study

Kang H, Liu Z, Huang B, Liang S, Yang K, Liu H, Lu M, Yan R, Chen X, Xu E

Journal of Hepatocellular Carcinoma 2025, 12:949-960

Published Date: 12 May 2025

Original Research

Machine Learning Radiomics for Predicting Response to MR-Guided Radiotherapy in Unresectable Hepatocellular Carcinoma: A Multicenter Cohort Study

Su K, Liu X, Zeng YC, Xu J, Li H, Wang H, Du S, Wang H, Yue J, Yin Y, Li Z

Journal of Hepatocellular Carcinoma 2025, 12:933-947

Published Date: 9 May 2025

Original Research

Decoding ARF4 and EIF5B-Based Prognostic Signatures and Immune Landscape Following Insufficient Radiofrequency Ablation in Hepatocellular Carcinoma: Through Multi-Omics and Experimental Validation

Zhang Y, Lu Y, Zheng S, Luo W, Tan M, Luo B

Journal of Hepatocellular Carcinoma 2025, 12:909-931

Published Date: 9 May 2025

Original Research

NRF1-Induced lncRNA DDX11-AS1 Contributes to the Progression of Hepatocellular Carcinoma via Activating CA9 Expression and the MEK/ERK Pathway

Li Y, Shi M, Bie B, Tian H, Li J, Li Z, Sun J

Journal of Hepatocellular Carcinoma 2025, 12:891-908

Published Date: 7 May 2025

Original Research

Effectiveness of Minimally Invasive Hepatectomy in Patients with Early or Intermediate-Stage Hepatocellular Carcinoma: A Multi-Institutional Cohort Study in an Asian Population

Chen HK, Chang KC, Shao SC, Soong RS, Chen YC, Wu CF, Wu TH, Chou TS, Chan SC, Lai ECC

Journal of Hepatocellular Carcinoma 2025, 12:879-890

Published Date: 7 May 2025

Original Research

Post-TACE ALBI-Score Trajectory in Intermediate and Advanced Hepatocellular Carcinoma: Prognostic Implications and Influencing Factors Analysis

Li J, Feng T, Cui C, Wang H, Su T, Jin L, Zhao X, Xiao W

Journal of Hepatocellular Carcinoma 2025, 12:865-878

Published Date: 5 May 2025

Original Research

Prognostic Significance of Elevated Platelet Count (>200 x 10^9 per L) in BCLC Stages B and C of Hepatocellular Carcinoma: A Retrospective Multicenter Analysis

Munker S, Rodriguez I, Bernhart K, Ben Khaled N, Findik M, Siegmund LK, Ye L, Reiter FP, Roessler D, Nasseh D, Balcar L, Pomej K, Scheiner B, Weiss C, Pinter M, Seidensticker M, Mayerle J, Philipp AB, De Toni EN

Journal of Hepatocellular Carcinoma 2025, 12:855-864

Published Date: 5 May 2025

Review

The Synergistic Mechanisms and Prospects of Transarterial Chemoembolization Combined with Immunotherapy for Hepatocellular Carcinoma

Chen QF, Chen S, Zhao M

Journal of Hepatocellular Carcinoma 2025, 12:841-854

Published Date: 30 April 2025

Perspectives

Hepatic Arterial Infusion Chemotherapy for Hepatocellular Carcinoma: A Three-Dimensional Visualization Perspective

Tan Y, Li PP, Liu H, Zhu JY, Wu QS

Journal of Hepatocellular Carcinoma 2025, 12:837-840

Published Date: 28 April 2025

Original Research

The Impact of Microwave Ablation on Recurrence and Metastasis of Hepatocellular Carcinoma: Insights From Animal Studies and Cytokine Profiling

Wang Y, Tan H, Wen C, Chen S, Zheng G, Qi H, Xie L, Shen L, Cao F, Fan W

Journal of Hepatocellular Carcinoma 2025, 12:825-835

Published Date: 26 April 2025

Original Research

A Novel Prognostic Signature Integrating Immune and Glycolytic Pathways for Enhanced Prognosis and Immunotherapy Prediction in Hepatocellular Carcinoma

Zhang Z, Zhao H, Wang P, Geng X, Yin M, Liu Y, Zhang S, Liang Y, Ji J, Zheng G

Journal of Hepatocellular Carcinoma 2025, 12:805-823

Published Date: 18 April 2025

Original Research

Atezolizumab Plus Bevacizumab in Patients with Unresectable Hepatocellular Carcinoma: Real-World Experience From a US Community Oncology Network

Cosgrove D, Tan R, Osterland AJ, Hernandez S, Ogale S, Mahrus S, Murphy J, Wilson T, Patton G, Loaiza-Bonilla A, Singal AG

Journal of Hepatocellular Carcinoma 2025, 12:791-804

Published Date: 18 April 2025

Review

Optimizing Treatment Selection for Early Hepatocellular Carcinoma Based on Tumor Biology, Liver Function, and Patient Status

Li X, Xu Y, Ou Y, Li H, Xu W

Journal of Hepatocellular Carcinoma 2025, 12:777-790

Published Date: 16 April 2025

Original Research

A Novel Nomogram Model for Predicting the Risk of Hepatocellular Carcinoma in Patients with Chronic Hepatitis B Infection

Wu Y, Wang M, Zhang Z, Chen G, Zhang B

Journal of Hepatocellular Carcinoma 2025, 12:765-775

Published Date: 16 April 2025

Original Research

Prognostic Analysis of Elderly Patients with Hepatocellular Carcinoma: an Exploration and Machine Learning Model Prediction Based on Age Stratification and Surgical Approach

Cai C, Zhu H, Li B, Tang C, Ren Y, Guo Y, Li J, Wang L, Li D, Li D

Journal of Hepatocellular Carcinoma 2025, 12:747-764

Published Date: 14 April 2025

Original Research

Serum Osteopontin Enhances Hepatocellular Carcinoma Diagnosis and Predicts Anti-PD-L1 Immunotherapy Benefit

Wu M, Zou F, He S, Pi Y, Song Y, Chen S, Li L

Journal of Hepatocellular Carcinoma 2025, 12:729-745

Published Date: 13 April 2025

Original Research

Preoperative Prediction of Macrotrabecular-Massive Hepatocellular Carcinoma Using Machine Learning-Based Ultrasomics

Li Y, Duan S, Ren S, Li D, Ma Y, Bu D, Liu Y, Li X, Cai X, Zhang L

Journal of Hepatocellular Carcinoma 2025, 12:715-727

Published Date: 12 April 2025

Case report

Rare Gingival Metastasis Occurring After Conversion Therapy Followed by Resection of Initially Unresectable Hepatocellular Carcinoma: A Case Report

Zhan J, Huang H, Zhan T, Liu X, Cheng Q

Journal of Hepatocellular Carcinoma 2025, 12:705-713

Published Date: 9 April 2025

Original Research

Identification of FDFT1 and PGRMC1 as New Biomarkers in Nonalcoholic Steatohepatitis (NASH)-Related Hepatocellular Carcinoma by Deep Learning

Liu Q, Yang Y, Wang Y, Wei S, Yang L, Liu T, Yu Z, Feng Y, Yao P, Zhu Q

Journal of Hepatocellular Carcinoma 2025, 12:685-704

Published Date: 5 April 2025

Original Research

ALBI Grade Enables Risk Stratification for Bleeding Events and Refines Prognostic Prediction in Advanced HCC Following Atezolizumab and Bevacizumab

Stefanini B, Fulgenzi CAM, Scheiner B, Korolewicz J, Cheon J, Nishida N, Ang C, Marron TU, Wu YL, Saeed A, Wietharn B, Rimassa L, Pirozzi A, Cammarota A, Pressiani T, Pinter M, Balcar L, Huang YH, Mehan A, Phen S, Vivaldi C, Salani F, Masi G, Bettinger D, Vogel A, Schönlein M, von Felden J, Schulze K, Wege H, Samson A, Galle PR, Kudo M, Manfredi GF, Celsa C, Awosika N, Cortellini A, Singal AG, Sharma R, Chon HJ, Tovoli F, Piscaglia F, Pinato DJ, D’Alessio A

Journal of Hepatocellular Carcinoma 2025, 12:671-683

Published Date: 4 April 2025

Original Research

Machine Learning-Based Model Used for Predicting the Risk of Hepatocellular Carcinoma in Patients with Chronic Hepatitis B

Wu T, Yan J, Xiong F, Liu X, Zhou Y, Ji X, Meng P, Jiang Y, Hou Y

Journal of Hepatocellular Carcinoma 2025, 12:659-670

Published Date: 3 April 2025

Editorial

Access to Medical Research is a Basic Human Right: A Roadmap to Research Integration Into a Practical Hepatocellular Carcinoma Treatment Allocation Algorithm (HCC-TAA)

Kaseb AO

Journal of Hepatocellular Carcinoma 2025, 12:649-657

Published Date: 28 March 2025

Original Research

The Expression of Ferroptosis-Related Genes in Hepatocellular Carcinoma and Their Relationships With Prognosis

Li H, Hu X, Wang L, Gu X, Chen S, Tang Y, Chen Y, Chen J, Yuan Z, Wang Y

Journal of Hepatocellular Carcinoma 2025, 12:629-648

Published Date: 20 March 2025

Original Research

Prediction Model of Survival in Unresectable HCC with Central Bile Duct Invasion Receiving TACE After Biliary Drainage: TEMP Score

Fan W, Zheng X, Zhang W, Zhu B, Wu Y, Xue M, Tang R, Huang Z, Qiao L, Lu M, Wu J, Tang Y, Chen J, Huang S, Bai M, Li J

Journal of Hepatocellular Carcinoma 2025, 12:615-628

Published Date: 20 March 2025

Original Research

Study on the Mechanism of QRICH1 Mediating PRMT1 to Regulate the Arginine Methylation Modification of cGAS to Promote Arsenics-Induced Pyroptosis in Hepatocellular Carcinoma Cells

Zhang J, Tian T, Tian S, Yao J, Zhang Y, Xie R, Yang T, Han B

Journal of Hepatocellular Carcinoma 2025, 12:597-614

Published Date: 19 March 2025

Original Research

A Chemotherapy Response-Related Gene Signature and DNAJC8 as Key Mediators of Hepatocellular Carcinoma Progression and Drug Resistance

Ye Y, Zeng Y, Huang S, Zhu C, Wang Q

Journal of Hepatocellular Carcinoma 2025, 12:579-595

Published Date: 20 March 2025

Original Research

Combined TACE with Targeted and Immunotherapy versus TACE Alone Improves DFS in HCC with MVI: A Multicenter Propensity Score Matching Study

Chen X, Wu X, Peng W, Liu L, Liu X, Wan X, Xu H, Zheng Y, Zhao H, Mao Y, Lu X, Sang X, Chang X, Zhou K, Pan J, Guan M, Hu D, Tan H, Zhang Y, Du S

Journal of Hepatocellular Carcinoma 2025, 12:561-577

Published Date: 19 March 2025

Rapid Communication

Radiation Segmentectomy or Ablative External Beam Radiation Therapy as Initial Treatment for Solitary Hepatocellular Carcinoma: A Multicenter Experience

De la Garza-Ramos C, Montazeri SA, LeGout JD, Lewis AR, Frey GT, Paz-Fumagalli R, Hallemeier CL, Rutenberg MS, Ashman JB, Toskich BB

Journal of Hepatocellular Carcinoma 2025, 12:553-559

Published Date: 13 March 2025

Original Research

Lasso-Based Nomogram for Predicting Early Recurrence Following Radical Resection in Hepatocellular Carcinoma

Zheng G, Zheng M, Hu P, Zhu Y, Zhang W, Zhang F

Journal of Hepatocellular Carcinoma 2025, 12:539-552

Published Date: 12 March 2025

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