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ISSN: 1178-2021


Archive: Volume 21, 2025

An Effectiveness Trial of an Exercise Physiologist Service to Improve Quality of Life in Adults with Severe Mental Illness: Protocol for the MOVEMENT Study

Chapman JJ, Siskind D, Yung AR, Lee YY, Arnautovska U, Scott JG, Burke K, Malacova E, Korman N, Wyder M, Doohan MA, Keating SE, Parker S, Walker ME, Hu D, O’Brien J, Lau G, Pratt GF, Rosenbaum S, Curtis J, Chatterton ML, Simmons L, Wheeler AJ

Neuropsychiatric Disease and Treatment 2025, 21:1399-1408

Published Date: 11 July 2025

Efficacy and Safety of Toludesvenlafaxine Hydrochloride Sustained-Release Tablets on Somatic Symptoms of Major Depressive Disorder: A Prospective, Single-Arm, Multicenter Clinical Study

Wang Y, He M, Zhang H, Luo Y, Sun X, Yao Z, Tang H, Yan R, Du X, Li Z, Peng D, Wang Z

Neuropsychiatric Disease and Treatment 2025, 21:1387-1397

Published Date: 9 July 2025

Blood Uric Acid in Mild Cognitive Impairment: A Cross-Sectional Study of Older Chinese Adults

Xue L, Xiao X, Mao X, Zhang X, Liu Y, Wu B

Neuropsychiatric Disease and Treatment 2025, 21:1307-1314

Published Date: 28 June 2025

A Novel Digital Intervention to Facilitate Diabetes Self-Management Among People with Schizophrenia and Related Disorders: Development and Acceptability Testing of SMART

Arnautovska U, Ritchie G, Soole R, Menon A, Korman N, Milton A, Varnfield M, Kelly JT, Jansen PM, Baker A, Ireland D, Russell AW, Chapman J, Mulligan K, Hirani SP, Vitangcol KJ, McKeon G, Siskind D

Neuropsychiatric Disease and Treatment 2025, 21:1289-1305

Published Date: 26 June 2025

An Evaluation a PrEP-Focused HIV Prevention Intervention Tailored for Individuals with Opioid Use Disorder and Cognitive Dysfunction

Mistler CB, Huedo-Medina TB, Shrestha R, Gunstad J, Zelenev A, Copenhaver MM

Neuropsychiatric Disease and Treatment 2025, 21:1235-1248

Published Date: 24 June 2025

Long-Term Symptomatic and Functional Remission with Paliperidone Palmitate 6-Monthly Treatment in Schizophrenia: A 3-Year Post-Hoc Analysis

Hamilton JM, Johnston KL, Simples Jnr J, Turkoz I, Lim L, Antunes J, Obando C, Mattingly G

Neuropsychiatric Disease and Treatment 2025, 21:1203-1214

Published Date: 18 June 2025

Effects of Parental Attitudes in Childhood on Depressive Symptoms Through Trait Anxiety and Negative Life Events in Adult Volunteers

Hayashida T, Kikkawa M, Masuya J, Ono M, Ito S, Nibuya R, Takashio O, Tamada Y, Hashimoto N, Inoue T

Neuropsychiatric Disease and Treatment 2025, 21:1191-1201

Published Date: 15 June 2025

Human Neural Stem Cells Reduce Hypoxia-Ischemic Neurological Impairment Through the Regulation of Inflammatory M1/M2 Microglias in Rats

Ding YB, Zhao Y, Chen BY, Wang Q, Wang ZY, Luan Z, Yi B

Neuropsychiatric Disease and Treatment 2025, 21:1173-1190

Published Date: 9 June 2025

Dynamic Changes in ALFF and DC in Subthreshold Depression Before and After ICBT Intervention

Wang Y, Ying Y, Zhu Z, Wang L, Yang Y, Zhang L, Yu W, Liang Y, Zhang H, Ji Y, Pan Y

Neuropsychiatric Disease and Treatment 2025, 21:1161-1172

Published Date: 7 June 2025

Association Between Daytime Sleepiness and Quality of Life in Chinese Adolescents: A Moderated Mediation of Cognitive Dysfunction and Depressive Symptoms

Li W, Hu N, Yang X, Zheng W, Tong J, Song J, Song Y, Gao X, Wang Z, Liu W, Wang L, Tan Y, Wang C, Deng H

Neuropsychiatric Disease and Treatment 2025, 21:1143-1159

Published Date: 3 June 2025

Auto-Immune Glial Fibrillary Acidic Protein Astrocytopathy with Active Intrathecal Epstein-Barr Virus: A Single-Center Case Series Report

Yu X, Zou Y, Li M, Wang L, Feng W, Wei L, Yang L, He J, Bu H, Li Y

Neuropsychiatric Disease and Treatment 2025, 21:1119-1130

Published Date: 31 May 2025

Alterations in White Matter Structure in Sleep-Related Epilepsies: A TBSS-Based Diffusion Tensor Imaging Study

Wang Z, Liu W, Feng X, Wang Q, Ning X, Xing W

Neuropsychiatric Disease and Treatment 2025, 21:1109-1118

Published Date: 30 May 2025

Network Analysis of Anxiety, Insomnia, Depression, and Suicide Attempts in Chinese Outpatients with Somatic Symptom Disorder

Fang J, Tang H, Liao H, Zhong Y, Li Y, Liao Y, Li Y

Neuropsychiatric Disease and Treatment 2025, 21:1091-1105

Published Date: 22 May 2025

Machine Learning Based Early Diagnosis of ADHD with SHAP Value Interpretation: A Retrospective Observational Study

Zhang X, Xiao X, Luo Y, Xiao W, Cao Y, Chang Y, Wu D, Xu H, Zhao J, Deng X, Jiang Y, Xie R, Liu Y

Neuropsychiatric Disease and Treatment 2025, 21:1075-1090

Published Date: 21 May 2025

Alterations of Blood Plasma Metabolites, Including Kynurenine and Tryptophan, in Bipolar Disorder

Nakayama T, Umehara H, Mawatari K, Tomioka Y, Yoshida T, Matsuda H, Matsumoto Y, Masuda R, Kamishikiryo T, Fuchikami M, Nakataki M, Takahashi A, Tajima A, Okada G, Numata S

Neuropsychiatric Disease and Treatment 2025, 21:1067-1073

Published Date: 18 May 2025

The Roles of Heart Rate Variability in Cerebral Stroke

Wang H, Jiang J, Zhou G, Zhang Y

Neuropsychiatric Disease and Treatment 2025, 21:1057-1065

Published Date: 16 May 2025

Association of Exposure to Humidex with Schizophrenia Admissions in Qingdao, China: A Time-Series Study

Han H, Liu J, Wang L, Li G, Wang T

Neuropsychiatric Disease and Treatment 2025, 21:989-997

Published Date: 29 April 2025

Potential Inflammatory Biomarkers and Differential Gut Microbiota in Cognitive Impairment After Ischemic Stroke

Wu L, Jiang Y, Xu W, Wang L, Li L, Zhang C, Huang K, Yang Y, Dai J, Zhou F

Neuropsychiatric Disease and Treatment 2025, 21:965-972

Published Date: 28 April 2025

Beyond Anxiety and Depression: Multidimensional Psychiatric Screening for Neurological Patients Based on HADS and BSI-53

Kujovic M, Benz D, Baumann B, Engelke C, Margittai Z, Christl J, Seitz RJ, Menge T, Bahr C, Riesbeck M, Meisenzahl E, Schmidt-Kraepelin C

Neuropsychiatric Disease and Treatment 2025, 21:955-964

Published Date: 26 April 2025

Associations of Vocal Features, Psychiatric Symptoms, and Cognitive Functions in Schizophrenia

Natsuyama T, Chibaatar E, Shibata Y, Okamoto N, Cruz Victorino JN, Ikenouchi A, Shibata T, Yoshimura R

Neuropsychiatric Disease and Treatment 2025, 21:943-954

Published Date: 23 April 2025

Exploration of Epigenetic Mechanisms and Biomarkers Among Patients with Very-Late-Onset Schizophrenia-Like Psychosis

Gan Y, Yue W, Sun J, Yang D, Fang C, Zhou Z, Yin J, Zhou H

Neuropsychiatric Disease and Treatment 2025, 21:927-942

Published Date: 22 April 2025

An Event-Related Potential Study on Facial Recognition in Children with and without Autism Spectrum Disorders

Deng JR, Tong M, Zhang XT, Lin ZP, Wang Z, Long J, Chen ZM

Neuropsychiatric Disease and Treatment 2025, 21:903-916

Published Date: 15 April 2025

Prevalence and Associated Factors of Depression in Patients with Ischaemic Stroke: A Cross-Sectional Study

Li Y, Qin W, Chen Y, Zhang D, Zhao Y

Neuropsychiatric Disease and Treatment 2025, 21:875-883

Published Date: 14 April 2025

The 4977 Bp Deletion of Mitochondrial DNA as a Potential Trait Marker for Major Depressive Disorder

He Y, Yang X, Li Z, Liu W, Tang J, Chen X

Neuropsychiatric Disease and Treatment 2025, 21:867-873

Published Date: 13 April 2025

Biomarkers of Suicidal Ideation in Depression: Insights From VMHC Analysis and Machine Learning

Wang X, Liu F, Hu X, Zhang Q, Guan X, Wu J, Long X, Lu Z

Neuropsychiatric Disease and Treatment 2025, 21:855-865

Published Date: 13 April 2025

Disruption of Multimodal Brain Networks and Structural-Functional Coupling in Adolescents with Major Depressive Disorder

Wang Y, Wei J, Yan Y, Wang M, Fan H, Du Y, Yang X, Ma X, Ma X

Neuropsychiatric Disease and Treatment 2025, 21:791-798

Published Date: 9 April 2025

Psychological Disturbances and Associated Risk Factors in Chinese Mine Rescuers: A Cross-Sectional Study

Hou Y, Meng Y, Wu F, Yang S, Yang F

Neuropsychiatric Disease and Treatment 2025, 21:751-760

Published Date: 5 April 2025

Exogenous GABA Alleviates Tourette Syndrome-Like Behavior in Sprague-Dawley Rats by Altering Gut Microbiota and Striatum Metabolism

Xu Y, Li LN, He XJ, Wang S, Li X, Feng H, Zhang HF, Song L, Shi HS, Tian XY

Neuropsychiatric Disease and Treatment 2025, 21:711-727

Published Date: 4 April 2025

Genotypic and Phenotypic Characteristics of Pediatric X-Adrenoleukodystrophy in a Chinese Cohort

Zhang Y, Shi X, Huang J, Wang C, Wu S, Tian G, Jia J, Chen Y

Neuropsychiatric Disease and Treatment 2025, 21:677-687

Published Date: 27 March 2025

Direct and Indirect Effects of Risk Perception and Risk Information on PTSD in Frontline Healthcare Workers

Wu L, Geng S, Zhou Y, Jiao R, Ouyang H, Cheng S, Shang Z, Yan W, Wang J, Jia Y, Li X, Liu W

Neuropsychiatric Disease and Treatment 2025, 21:663-676

Published Date: 21 March 2025

Anxiolytic, Antidepressant and Healthy Sleep-Promoting Potential of Rosmarinic Acid: Mechanisms and Molecular Targets

Priya V, Srinivasan D, Priyadarsini S, Dabaghzadeh F, Rana SS, Chengaiyan JG, Sudesh R, Ahmad F

Neuropsychiatric Disease and Treatment 2025, 21:641-661

Published Date: 20 March 2025

A Pilot Study of Remote Ischemic Conditioning in Preventing Post-Stroke Depression

Li W, Qin Y, Wang J, Li L, Gao J, Xu X, Wu Z, Ji X, Wang Y, Gao K, Ren M, Shao X

Neuropsychiatric Disease and Treatment 2025, 21:611-619

Published Date: 19 March 2025

Aripiprazole Lauroxil: Development and Evidence-Based Review of a Long-Acting Injectable Atypical Antipsychotic for the Treatment of Schizophrenia

Citrome L, Correll CU, Cutler AJ, Dunbar M, Hoberg AR, Hopkinson C, Mattingly GW, McGrory JA, Rege B, Weiden PJ, McDonnell D

Neuropsychiatric Disease and Treatment 2025, 21:575-596

Published Date: 14 March 2025

Environmental Factors in the Etiology of Mental Disorders in the Czech Republic: Final Results

Hosak L, Hurdova K, Hrnciarova J, Zapletalova J, Koncelikova D, Latalova K

Neuropsychiatric Disease and Treatment 2025, 21:541-545

Published Date: 12 March 2025

A Review of Clinical Advances and Challenges in Clozapine-Induced Myocarditis

Li M, Bai Y, Wang Y, Xing H, Zhang Y, Ding W, Ye H, Ma L, Wang W, Bao T

Neuropsychiatric Disease and Treatment 2025, 21:525-538

Published Date: 7 March 2025

The Correlation Between RIN3 Gene Methylation and Cognitive Impairment in Parkinson’s Disease

Yu X, Zhu K, Wang T, Li HY, Zhang X, Zhong X, Wang L

Neuropsychiatric Disease and Treatment 2025, 21:511-524

Published Date: 7 March 2025

Duration Mismatch Negativity in Adults With Autism Spectrum Disorder Versus Healthy Controls

Sato A, Itagaki S, Ohnishi T, Osakabe Y, Hoshino H, Kanno K, Suzutani K, Wada T, Miura I, Yabe H

Neuropsychiatric Disease and Treatment 2025, 21:503-510

Published Date: 5 March 2025

Optimal Treatment of Magnetic Seizure Therapy (MST) in Patients with Clozapine-Resistant Schizophrenia (CRS)

Xiang Q, Xu P, Zhai Z, Jia Y, Li C, Liu D

Neuropsychiatric Disease and Treatment 2025, 21:491-501

Published Date: 5 March 2025

Characteristics of Gut Microbiota and Plasma Metabolites in Patients with Post-Stroke Depression

Yan C, Si T, Zheng W, Huang L, Wen L, Shen H, Qu M

Neuropsychiatric Disease and Treatment 2025, 21:477-489

Published Date: 4 March 2025

The Prevalence of Tardive Dyskinesia In Patients With Schizophrenia Treated With Antipsychotics In Malaysia

Nedunjelian A, Ng CG, Lim PK, Sulaiman AH, Koh OH, Francis B

Neuropsychiatric Disease and Treatment 2025, 21:465-475

Published Date: 5 March 2025

Neuropsychiatric Disease and Treatment: 20 Years on

Pinder RM

Neuropsychiatric Disease and Treatment 2025, 21:463-464

Published Date: 1 March 2025

Neuropsychiatric Approaches to Essential and Functional Tremor: A Comparative Study

Balal M, Çakmak S, Erdem M, Demirkiran M

Neuropsychiatric Disease and Treatment 2025, 21:451-462

Published Date: 2 March 2025

Uncovering Potential Biomarkers and Constructing a Prediction Model Associated with Iron Metabolism in Parkinson’s Disease

Cheng Y, Zhai H, Liu Y, Yang Y, Fang B, Song M, Zhong P

Neuropsychiatric Disease and Treatment 2025, 21:437-449

Published Date: 28 February 2025

Activation of the Reelin/GSK-3β/p-Tau Signaling Pathway in the Hippocampus of Patients with Temporal Lobe Epilepsy

Lin J, Lin X, Fu YJ, Li X, Li X, Wang Y, Zhao L, Yu S, Piao YS

Neuropsychiatric Disease and Treatment 2025, 21:409-419

Published Date: 27 February 2025

Understanding Relapse in Bipolar Disorder at a Tertiary Mental Health Facility in Uganda

Kimbowa P, Nalwoga V, Namwanje S, Ssekulima JK, Anguparu SW

Neuropsychiatric Disease and Treatment 2025, 21:395-408

Published Date: 27 February 2025

Fibroblast Growth Factor 21 Protects Against Cerebral Ischemia/Reperfusion Injury by Inhibiting Oxidative Stress and Ferroptosis

Li J, Jiang H, Bai W, Yang Y, Zhou G, Chen W, Shao J

Neuropsychiatric Disease and Treatment 2025, 21:355-371

Published Date: 25 February 2025

Association of Blood Pressure with Neurological Function Decline and Functional Outcome in Patients of Watershed Infarction

Yang L, Zhang T, Liu X, Chen G, Ding P, Li W, Liao H, Yu D, Liu J, Yue W

Neuropsychiatric Disease and Treatment 2025, 21:335-346

Published Date: 19 February 2025

Efficacy of Magnetic Seizure Therapy in Patients with Schizophrenia and Combined fMRI-EEG to Explore the Regulatory Mechanisms of Brain Networks

Wei S, Chen B, Guo Z, Zhang H, Li J, Hu X, Yang C, Li J, Li X, Liu Z, Xu Y, Liu S

Neuropsychiatric Disease and Treatment 2025, 21:323-334

Published Date: 19 February 2025

Electroencephalogram (EEG) Based Prediction of Attention Deficit Hyperactivity Disorder (ADHD) Using Machine Learning

Kim JW, Kim BN, Kim JI, Yang CM, Kwon J

Neuropsychiatric Disease and Treatment 2025, 21:271-279

Published Date: 13 February 2025

The Effects of Hyperlipidemia on Postoperative Cognitive Dysfunction in Patients Undergoing Laparoscopic Gynecological Tumor Surgery

Shen H, Xiong Y, Liang Y, Liu Z, Guo L, Qin Y, He J, Lin F

Neuropsychiatric Disease and Treatment 2025, 21:259-269

Published Date: 13 February 2025

The Prevalence of Depression Among Parkinson’s Disease Patients in Saudi Arabia: A Cross-Sectional Study

Al-Qahtani Z, Alqahtani ASM, Alzuhairi AMS, Qarah M, Alqarni AA, Alqahtani AOM, AlShehri FAA, Alqathanin MAA, Alshahrani OMO, Alqahtani MAF, Mahmood SE

Neuropsychiatric Disease and Treatment 2025, 21:241-256

Published Date: 4 February 2025

Factors Affecting Negative Symptoms in Schizophrenia and Their Relationship with Anxiety and Depression

Zeng G, Liang R, Xiao L, Cao W, Zhou W, Wang W, Liu C, Zhou H, Shi X, Chen B, Chen W

Neuropsychiatric Disease and Treatment 2025, 21:229-240

Published Date: 4 February 2025

Characteristics of Parthenogenetic Stem Cells and Their Potential Treatment Strategy for Central Nervous System Diseases

Cai H, Huang J, Wang W, Lin W, Ahmed W, Lu D, Quan J, Chen L

Neuropsychiatric Disease and Treatment 2025, 21:213-227

Published Date: 3 February 2025

Research Progress on Neural Processing of Hand and Forearm Tactile Sensation: A Review Based on fMRI Research

Chen H, Fu S, Zhi X, Wang Y, Liu F, Li Y, Ren F, Zhang J, Ren L, Wang Y

Neuropsychiatric Disease and Treatment 2025, 21:193-212

Published Date: 31 January 2025

Differentiations in Illness Duration, Thyroid-Stimulating Hormone, Glucose and P300 Latency Between Drug-Naïve Unipolar and Bipolar Depression: A Comparative Cross-Sectional Study

Li C, Yang L, Zhang Q, Zhang Y, Li R, Jia F, Wang L, Ma X, Yao K, Tian H, Liu Z, Zhuo C

Neuropsychiatric Disease and Treatment 2025, 21:157-166

Published Date: 29 January 2025

Functional Remediation Improves Serum BDNF and TrkB Levels in Euthymic Patients with Bipolar Disorder: A Randomized Trial Study

Li R, Li J, Ji SS, Li D, Chu L, Zhang J, Sun X, Luo X, Zhang Y

Neuropsychiatric Disease and Treatment 2025, 21:115-128

Published Date: 25 January 2025

White Matter Injury in Central Nervous System Disorders

Zheng L, Wang X, Li P, Hao Y, Zhang H, Chen H, Zheng Z

Neuropsychiatric Disease and Treatment 2025, 21:107-114

Published Date: 24 January 2025

Clinical Utility of Zuranolone for Postpartum Depression: A Narrative Review

Giannopoulos A, Singh J, Deligiannidis KM

Neuropsychiatric Disease and Treatment 2025, 21:93-105

Published Date: 25 January 2025

Multimodal Magnetic Resonance Findings in Parkinson’s Disease With “Antecedent Essential Tremor”: A Case Series of a Large Kindred

Kong Y, Yao L, Xiao X, Chen A, Wang K, Yan H, Sun R, Liu R, Kong Q

Neuropsychiatric Disease and Treatment 2025, 21:79-92

Published Date: 22 January 2025

Cognitive Disorders In Acquired Sensorineural Hearing Loss, At The Ent Department Of The “Village Bondeko” Center, In Kinshasa

Masamba GR, Sokolo Gedikondele J, Longo-Mbenza B, Nganga Nkanga MS, Matanda Nzanza R, Matonda-ma-Nzuzi T, Ikanga J, Nge Okwe A, Lema Mabwaka G, Mawalala Malengele H, Nangi Mampuya C, Lumbu Malundama D

Neuropsychiatric Disease and Treatment 2025, 21:37-52

Published Date: 7 January 2025

Relationship Between Anxiety Symptoms and Age-Related Differences in Tic Severity

Lei T, Yang K, Jun J, Hu S, Yang Q, Hong X, Cui Y

Neuropsychiatric Disease and Treatment 2025, 21:25-36

Published Date: 6 January 2025

The Association of Mitochondrial tRNACys G5783A Mutation with Major Depressive Disorder in Two Han Chinese Families

Jing P, Yu H, Sun W, Liang M, Xia T, Yang H, Chen P, Li J, Zhang X

Neuropsychiatric Disease and Treatment 2025, 21:15-24

Published Date: 3 January 2025